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News Archive - Mario Aguilera

Faulty DNA Disposal System Causes Inflammation

February 8, 2024

Each cell features mtDNA, instructions that mitochondria use to create energy. When mtDNA remains where it belongs, cells remain healthy. But when it goes where it doesn’t belong, mtDNA can initiate an immune response and inflammation. Scientists have discovered the pathways behind this process.

Extra Fingers and Hearts: Pinpointing Changes to Our Genetic Instructions That Disrupt Development

February 6, 2024

UC San Diego scientists have shown that they can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts.

UC San Diego Is Now a Bee Campus. Here’s What that Means…

January 11, 2024

UC San Diego recently became a Bee Campus USA member, part of a national program created to support pollinating organisms, boost the abundance of native plant species and reduce pesticide use. Professor James Nieh explains what the designation means for UC San Diego and the San Diego region.

Inside the Matrix: Nanoscale Patterns Revealed Within Model Research Organism

December 21, 2023

Following years of research and the power of a technologically advanced instrument, UC San Diego scientists have detailed the complex nanoscale exoskeleton patterns of the roundworm, a model laboratory organism, revealing clues about how skin layers are bound together.

Wildfires Also Impact Aquatic Ecosystems

December 12, 2023

Researchers have shown that the effects of wildfires are not limited to terrestrial ecosystems. Aquatic ecosystems are also undergoing rapid changes. The study found that fire debris transforms lakes and other aquatic ecosystems, with implications for fisheries and water quality.

Bacteria-Virus Arms Race Provides Rare Window into Rapid and Complex Evolution

November 9, 2023

Rather than a slow, gradual process as Darwin envisioned, biologists can now see how evolutionary changes unfold on accelerated timescales. Using an arms race between bacteria and viruses, researchers are documenting complex evolutionary processes in simple laboratory flasks in only three weeks.

What Happens When We Pass Out? Researchers ID New Brain and Heart Connections

November 1, 2023

UC San Diego researchers have for the first time identified the genetic pathway between the heart and brain tied to fainting. In a new study published in the journal Nature, they found that vagal sensory neurons trigger fainting, laying a foundation for addressing fainting-related disorders.

How Do We Teach Science? UC San Diego Launches STEM Education Research Program

October 12, 2023

UC San Diego has launched one of the only programs aimed at training students in the emerging field of STEM research education. The new program gives undergraduate students coveted research experience while also asking them to think critically about how science is taught and to whom.

Innovative Researchers earn NIH New Innovator Awards

October 3, 2023

Two early career researchers at UC San Diego have been named recipients of the 2023 National Institutes of Health Director’s New Innovator Award.

Enhancing Immune Defenses: Researchers Unveil the Secrets of Specialized T Cells to Conquer Tumors

August 30, 2023

Immunologists have uncovered new approaches to enhance protection from tumors and infections. They have revealed new insights into the metabolism of specialized cells of the immune system known as tissue-resident CD8 T cells and how they could be enhanced as immune defense weapons against tumors.
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